Epidermal Growth Factor, EGF

Epidermal growth factor (EGF) receptor kinase-independent signaling by EGF.

The ErbB family of receptors, which includes the epidermal growth factor receptor (EGFR), ErbB2, ErbB3, and ErbB4, mediate signaling by EGF-like polypeptides. To better understand the role of the EGFR tyrosine kinase, we analyzed signaling by a kinase-inactive EGFR (K721M) in ErbB-devoid 32D cells. K721M alone exhibited no detectable signaling capacity, whereas coexpression of K721M with ErbB2,...

Fetal Thymocyte Growth and Differentiation: Epidermal Growth Factor (EGF) Modulates

Assessment of Epidermal Growth Factor (EGF) Effects on Development of Vitrified Mouse Morulae to the Blastocyst Stage

Many investigators are interested in finding the new cultural systems that can support the in vitro development of pre-implantation embryos better. Previous studies suggested that growth factors such as epidermal growth factor (EGF) are important in pre-implantation embryo development and implantation process. On the other hand, it is very important to support post thaw development of frozen em...

Transgenic Soybean Production of Bioactive Human Epidermal Growth Factor (EGF)

Necrotizing enterocolitis (NEC) is a devastating condition of premature infants that results from the gut microbiome invading immature intestinal tissues. This results in a life-threatening disease that is frequently treated with the surgical removal of diseased and dead tissues. Epidermal growth factor (EGF), typically found in bodily fluids, such as amniotic fluid, salvia and mother's breast ...

Vascular Endothelial Growth Factor (VEGF) and Epidermal Growth Factor (EGF) in Papillary Thyroid Cancer

Early diagnosis and radical management of thyroid cancer do not always result in curing the patient. Long-term analyses of deaths due to thyroid cancer have allowed for establishing systems for distinguishing increased risk groups, such as AMES or AGES. These commonly employed prognostic systems recognize the role of four basic factors only (age, stage, extent of the tumor, its size [AGES] and ...